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29224100
ORGANIC CHEMICALS›Oxygen-function amino-compounds

Lysine and its esters; salts thereof

Standard EU duty
0%
VAT
23%
Additional duties / sanctions
0 rules
Docs required
46 docs
7P237P24C669C670C672Y923+40
Standard rates
Applies toTypeRateConditionsRegulation
ERGA OMNESThird country duty6.3%—R3115/94
ERGA OMNES (excl. CN)Anti-dumping/countervailing statistic——R1330/25
CNDefinitive anti-dumping duty58.2%—R1330/25
CNDefinitive anti-dumping dutySee notes2 condition(s)R1330/25
CNDefinitive anti-dumping dutySee notes2 condition(s)R1330/25
CNDefinitive anti-dumping dutySee notes2 condition(s)R1330/25
CNDefinitive anti-dumping dutySee notes2 condition(s)R1330/25
CNDefinitive anti-dumping dutySee notes2 condition(s)R1330/25
CNDefinitive anti-dumping dutySee notes2 condition(s)R1330/25
TRAnti-dumping/countervailing duty - ControlSee notes—D0142/96
Preferences
ERGA OMNES 0%ERGA OMNES 0%AD 0%AL 0%BA 0%CA 0%CAMER 0%CARI 0%CH 0%CI 0%CL 0%CM 0%CO 0%DZ 0%EBA 0%EC 0%EEA 0%EG 0%EH 0%ESA 0%EUCA 0%FJ 0%FO 0%GB 0%GE 0%GH 0%GSP 2.8%GSP+ 0%IL 0%JO 0%JP 0%KE 0%KR 0%LB 0%LOMB 0%MA 0%MD 0%ME 0%MK 0%MX 0%NZ 0%PE 0%PG 0%PS 0%SADC EPA 0%SB 0%SG 0%SM 0%SWITZ 0%SY 0%TN 0%TR 0%UA 0%VN 0%WS 0%XC 0%XK 0%XL 0%XS 0%ZA 0%
Notes
TM5101. Customs duties shall be suspended in respect of goods intended for incorporation in the ships, boats or other vessels classified at the following CN codes 8901 10 10; 8901 20 10; 8901 30 10; 8901 90 10; 8902 00 10; 8903 91 10; 8903 92 10; 8904 00 10; 8904 00 91; 8905 10 10; 8905 90 10; 8906 10 00; 8906 90 10 for the purposes of their construction, repair, maintenance or conversion, and in respect of goods intended for fitting to or equipping such ships, boats or other vessels.2. Customs duties shall be suspended in respect of:(a) goods intended for incorporation in drilling or production platforms:(1) fixed, of subheading ex 8430 49, operating in or outside the territorial sea of Member States, or(2) floating or submersible, of subheading 8905 20, for the purposes of their construction, repair, maintenance or conversion, and in respect of goods intended for equipping the said platforms.(b) tubes, pipes, cables and their connection pieces, linking these drilling or production platforms to the mainland.
EU003According to The Special Provisions of Section II (A) (3) of the Preliminary Provisions of the Combined Nomenclature the suspension of customs duties for goods for certain categories of ships, boats and other vessels and for drilling or production platforms shall be subject to conditions laid down in the relevant provisions of the European Union with a view to customs control of the use of such goods.
CD813The application of the individual duty rate for this company shall be conditional upon presentation to the Member States’ customs authorities of a valid commercial invoice, on which shall appear a declaration dated and signed by an official of the entity issuing such invoice, identified by his/her name and function, drafted as follows: ‘I, the undersigned, certify that the (volume in tonnes) of lysine sold for export to the European Union covered by this invoice was manufactured by (company name and address) (TARIC additional code) in the People’s Republic of China. I declare that the information provided in this invoice is complete and correct.’ Until such invoice is presented, the duty applicable to all other imports originating in the People’s Republic of China shall apply.
CD813The application of the individual duty rate for this company shall be conditional upon presentation to the Member States’ customs authorities of a valid commercial invoice, on which shall appear a declaration dated and signed by an official of the entity issuing such invoice, identified by his/her name and function, drafted as follows: ‘I, the undersigned, certify that the (volume in tonnes) of lysine sold for export to the European Union covered by this invoice was manufactured by (company name and address) (TARIC additional code) in the People’s Republic of China. I declare that the information provided in this invoice is complete and correct.’ Until such invoice is presented, the duty applicable to all other imports originating in the People’s Republic of China shall apply.
CD813The application of the individual duty rate for this company shall be conditional upon presentation to the Member States’ customs authorities of a valid commercial invoice, on which shall appear a declaration dated and signed by an official of the entity issuing such invoice, identified by his/her name and function, drafted as follows: ‘I, the undersigned, certify that the (volume in tonnes) of lysine sold for export to the European Union covered by this invoice was manufactured by (company name and address) (TARIC additional code) in the People’s Republic of China. I declare that the information provided in this invoice is complete and correct.’ Until such invoice is presented, the duty applicable to all other imports originating in the People’s Republic of China shall apply.
CD813The application of the individual duty rate for this company shall be conditional upon presentation to the Member States’ customs authorities of a valid commercial invoice, on which shall appear a declaration dated and signed by an official of the entity issuing such invoice, identified by his/her name and function, drafted as follows: ‘I, the undersigned, certify that the (volume in tonnes) of lysine sold for export to the European Union covered by this invoice was manufactured by (company name and address) (TARIC additional code) in the People’s Republic of China. I declare that the information provided in this invoice is complete and correct.’ Until such invoice is presented, the duty applicable to all other imports originating in the People’s Republic of China shall apply.
CD813The application of the individual duty rate for this company shall be conditional upon presentation to the Member States’ customs authorities of a valid commercial invoice, on which shall appear a declaration dated and signed by an official of the entity issuing such invoice, identified by his/her name and function, drafted as follows: ‘I, the undersigned, certify that the (volume in tonnes) of lysine sold for export to the European Union covered by this invoice was manufactured by (company name and address) (TARIC additional code) in the People’s Republic of China. I declare that the information provided in this invoice is complete and correct.’ Until such invoice is presented, the duty applicable to all other imports originating in the People’s Republic of China shall apply.
CD813The application of the individual duty rate for this company shall be conditional upon presentation to the Member States’ customs authorities of a valid commercial invoice, on which shall appear a declaration dated and signed by an official of the entity issuing such invoice, identified by his/her name and function, drafted as follows: ‘I, the undersigned, certify that the (volume in tonnes) of lysine sold for export to the European Union covered by this invoice was manufactured by (company name and address) (TARIC additional code) in the People’s Republic of China. I declare that the information provided in this invoice is complete and correct.’ Until such invoice is presented, the duty applicable to all other imports originating in the People’s Republic of China shall apply.
CD303The relief from or reduction of customs duties shall be subject to the specific request expressed by the declarant in box 44 "Additional information/Documents produced/Certificates and authorisations", of the Single Administrative Document (SAD)
TM904Preferences granted under the agreement between the European Union and Morocco in force from 19 July 2019.As of 3 October 2025, products originating in Western Sahara subject to controls by the customs authorities of the Kingdom of Morocco shall benefit from trade preferences under the terms of the new Agreement in the form of exchange of letters between the EU and Morocco, The European Union and the Kingdom of Morocco have agreed to allow those products to be identified by reference to the region of origin to be included in the proof of origin and as provided for in Protocol 4.In view of the application of these measures, the origin certificates codes U179 and U180 must be declared.The country code to be entered in the origin declaration when these proofs of origin are used is “EH”.
CD727Eligibility to benefit from this preference is subject to the presentation of an origin declaration stating the European Union origin of the goods, in the context of the Canada-European Union Comprehensive Economic and Trade Agreement (CETA).
CD906The list of non-eligible locations and their postal codes is available at the following address: http://ec.europa.eu/taxation_customs/customs/technical-arrangement_postal-codes.pdf
CD500Eligibility to benefit from this preference is subject to the presentation of a proof of origin stating the community origin of the goods, in the context of the agreement between the European Union and the Swiss Confederation.
TM303Anti-dumping/countervailing measures continue to apply to goods originating in the countries concerned even if imported from Türkiye.
5

Binding Tariff Information

BTI classification examples

DEgold968/25-1

Lysine aspartate salt, white crystalline powder

L-lizyno-L-asparaginianGRI 1GRI 6
ITgold025-0635

L-lysine-L-aspartate (lysine aspartate) powder

L-lizyna-L-asparaginian (sól lizyny)GRI 1GRI 6
ITgold025-0196

Lysine powder for animal feed

lizyna (aminokwas)GRI 1GRI 6
DEgold497/23-1

L-Isoleucin amino acid powder

tinGRI 1GRI 6
DEgold167/25-1

EDTA tetrasodium salt dihydrate

EDTA tetranatriumsalz dihydratGRI 1GRI 6

BTI (Binding Tariff Information) is an official EU customs decision confirming the classification of goods. Valid for 3 years, binding across all EU member states.

Classification scope and key substances

CN code 292241 covers lysine and its esters and salts — an essential exogenous amino acid for humans and animals, belonging to the group of basic alpha-amino acids. The principal commercial products in this group are L-lysine monohydrochloride (CAS 657-27-2), used as a feed additive to improve the amino acid balance of poultry, swine and aquaculture feeds, and L-lysine sulphate (CAS 60343-69-3), available as a fermentation concentrate with slightly lower purity and widely used in farm animal nutrition. Lysine is produced industrially by bacterial fermentation of starch-based raw materials (maize, tapioca, sugar) using Corynebacterium glutamicum strains. The global lysine market is concentrated — the leading suppliers are producers from China, Brazil, South Korea and Europe. Pursuant to Note 1 to Chapter 29, CN 292241 applies to L-lysine as a chemically defined compound in pure form or aqueous solution; concentrated fermentation broths must meet the applicable purity criteria, otherwise classification may fall in Chapter 23 as fermentation products for use in animal feeding.

REACH, CLP and feed regulatory requirements

L-lysine monohydrochloride and sulphate used as feed additives are regulated by Regulation (EC) No 1831/2003 on additives for use in animal nutrition. L-lysine monohydrochloride is entered in the EU Community Register of Feed Additives as an amino acid authorised for all animal species. Importers of feed-grade lysine into the EU must meet the following requirements: the additive must be authorised for the EU market, labelling and specifications must comply with Regulation (EC) No 767/2009 on the placing on the market of feed, and the non-EU supplier must be listed on the European Commission's register of approved third-country establishments for the import of feed. Under REACH, L-lysine used in animal feed applications may benefit from the exemption for substances used in animal nutrition under Article 2(2) of Regulation (EC) No 1907/2006, but registration is required for industrial and cosmetic applications. A Safety Data Sheet (SDS) prepared in accordance with Regulation (EU) 2020/878 should be available to all purchasers. The CLP classification of L-lysine indicates low hazard in standard commercial forms — powder may cause mechanical irritation to the eyes and respiratory tract (H319, H335), requiring basic personal protective measures.

Practical guidance for importers and exporters

The customs declaration for goods under CN 292241 should state the precise name (L-lysine monohydrochloride or L-lysine sulphate), the CAS number, degree of purity (typically 98–99% for the HCl form or 65–70% lysine content for the sulphate), quantity in tonnes and intended use (feed, food, pharmaceutical). Importation of feed-grade lysine into the EU requires a veterinary health certificate issued by the competent authority of the exporting country, confirming compliance with EU sanitary requirements, and prior notification in the TRACES system (Trade Control and Expert System) at the border inspection post (BIP). Importers must verify the registration status of the exporting establishment on the European Commission's list of approved feed suppliers. L-lysine used in food supplements for humans or fortified foods is subject to Regulation (EC) No 1925/2006 and must meet the purity standards of the European Pharmacopoeia or recognised standardisation body specifications. Preferential tariff rates may be available under FTA agreements with lysine-producing countries — verification in the TARIC database and use of preferential origin documents (EUR.1, REX) is recommended. Where classification between Chapter 23 (fermentation concentrates) and Chapter 29 is uncertain, a composition analysis and purity certificate are decisive.

Chemical safety and SDS requirements

Organic substances under CN code 2922 41 (Lysine and its esters) require detailed chemical documentation for customs clearance. The Safety Data Sheet must comply with REACH Annex II. Substances classified as hazardous under CLP require GHS pictogram labelling. Transport follows ADR (road) or IMDG (maritime) regulations. Some organic substances may be subject to export controls as dual-use goods. Importers should verify whether the substance requires REACH authorisation (Annex XIV) or is subject to restrictions (Annex XVII).

Frequently asked questions

Are L-lysine HCl and lysine sulphate always classified under CN 292241?
L-lysine monohydrochloride as a chemically defined amino acid salt (CAS 657-27-2) is generally classified under CN 292241. Lysine sulphate available as a fermentation concentrate with lower purity (approx. 65%) may be classified in Chapter 23 as a fermentation product for animal feed if it does not meet the purity criterion of Note 1 to Chapter 29. The degree of purity and commercial form, confirmed by a certificate of analysis, are the decisive factors.
What documents are required for importing feed-grade lysine into the EU?
Importing feed-grade lysine (CN 292241) into the EU requires: a veterinary health certificate issued by the competent authority of the exporting country, prior notification in the TRACES system, verification of the exporting establishment's status on the European Commission's approved feed supplier list, a certificate of analysis confirming composition and purity, a commercial invoice and transport document. The feed additive must be authorised on the EU market under Regulation (EC) No 1831/2003. Current customs requirements should be verified in the TARIC system.
Is lysine used in animal feed subject to REACH registration?
L-lysine and its salts used as animal feed ingredients are exempt from REACH registration obligations under Article 2(2) of Regulation (EC) No 1907/2006, which exempts substances used in animal nutrition governed by separate EU legislation (Regulation 1831/2003). However, REACH registration may be required for industrial and cosmetic applications. The importer should verify the scope of the exemption and the intended use of the goods before customs clearance.
How to classify Lysine and its esters in customs tariff 2922 41?
Classification of Lysine and its esters under CN code 2922 41 is based on chemical structure and functional groups. If in doubt, you can apply for a Binding Tariff Information (BTI) from the national customs authority.

Useful tools & resources

Customs calculators
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Related glossary terms
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